In the bloodstream, it travels to the kidneys to be eliminated. After being created in the liver, urea is excreted to the bloodstream. Urea is the waste product of protein breakdown carried out in the liver. The BUN test measures the nitrogen present in the waste product urea found within the blood. Some medicines may also induce low levels of blood urea nitrogen. Decreased blood urea levels are instead usually associated with liver damage, malnutrition, overhydration or a low-protein diet. Low Levels of Blood Urea NitrogenĪ lowered level of blood urea nitrogen is not as indicative of kidney issues as high levels. Some medicines can also instigate high levels of blood urea nitrogen. Additional factors include dehydration and a high-protein diet (more protein leads to more protein breakdown and consequently to more urea in the blood). For instance, internal bleeding or tissue damage may raise urea nitrogen in the blood. Other factors that cause high blood urea nitrogen may involve the respiratory, circulatory and gastrointestinal tracts.
A creatinine blood test in conjunction with a BUN test can help confirm kidney damage. Kidney disease or kidney injury can originate from multiple sources such as from high blood pressure and from diabetes. The most probable factor is kidney damage. Several factors can give rise to high levels of blood urea nitrogen, which are levels above the reference value. Levels outside of the normal values could also indicate that something is wrong with the way your liver is processing proteins. When the blood urea nitrogen values fall out of the reference range, it is very likely that there is some kind of abnormality in the body, most probably related to the kidney. In children, the healthy reference range is from 5 to 18 mg/dL or between 1.8 and 6.4 mmol/L. In adults, normal values are considered between 10 and 20 mg/dL, or between 3.6 and 7.1 mmol/L. whether the blood urea nitrogen levels fall within normal values. Blood Urea Nitrogen RangesĪs with multiple clinical assessments, the levels of urea nitrogen in the blood have been well studied and a reference range has been established to determine whether the kidney is healthy or not, i.e.
Both high and low blood urea nitrogen levels can be signs of body distress or disorders in specific body systems. Depending on the range of urea levels found within the blood, a doctor can make several determinations on how various body systems are functioning.
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